Guowei Huang

Professor

Department of Nutrition and Food Science,

School of Public Health

Tianjin Medical University

22 Qixiangtai Road

Tianjin 300070

Phone: +86-22-83336603

Email Address: huangguowei@tmu.edu.cn

Education

Ph.D., Food Science, Tianjin University of Science and Technology, Tianjin, China, 2009

M.S., Nutrition and Food Hygiene, Tianjin Medical University, Tianjin, China, 1989

B.S., Preventive Medicine, Tianjin Medical University, Tianjin, China, 1986

Professional Background

2005-  Professor, School of Public Health, Tianjin Medical University, Tianjin, China

2003-2004 Visiting Professor, Faculty of Medicine and Dentistry, University of Western Ontario, Canada

2000-2005 Professor, School of Public Health, Tianjin Medical University, Tianjin, China

1995-2000 Associate Professor, School of Public Health, Tianjin Medical University, Tianjin, China

1989-1995 Assistant and Lecturer, School of Public Health, Tianjin Medical University, Tianjin, China

Awards Received 

1.State Council Special Allowance Expert, 2015.

2.Outstanding Jinmen Scholar of Tianjin, 2020.

3.Tianjin Science and Technology Progress Second Prize (first author), 2021.

4.Second Prize of the National Teaching Achievement Award (first author), 2018.

5.Second Prize for National Excellent Textbook (Higher Education Category), 2021

Other Roles

1.Member, Teaching Instruction Committee of Preventive Medicine and Public Health of Ministry of Education, China

2.Executive Director, Chinese Nutrition Association 

3.Chairman, Nutrition and Neuroscience Branch, Chinese Nutrition Association

4.Vice Chairman, Tianjin Nutrition Association

5.Vice Chairman, Tianjin Health Management Association

6.Co-editor, Asia Pacific Journal of Clinical Nutrition

7.Editorial Board Member, Journal of Nutritional Biochemistry, 

8.Editorial Board Member, Acta Nutrimenta Sinica

9.Editorial Board Member, Chinese Journal of Preventive Medicine

Publications

1.Duan H#, Zhou D#, Xu N, Yang T, Wu Q, Wang Z, Sun Y, Li Z, Li W, Ma F, Chen Y, Du Y, Zhang M, Yan J, Sun C, Wang G, Huang G*. Association of unhealthy lifestyle and genetic risk factors with mild cognitive impairment in Chinese older adults. JAMA Network Open, 2023, 6(7): e2324031. 

2.H Duan, X He, T Yang, N Xu, Z Wang, Z Li, Y Chen, Y Du, M Zhang, J Yan, C Sun, G Wang, F Ma, W Li*, X Li*, G Huang*. Critical Values of Daily Sedentary Time and Its Longitudinal Association with Mild Cognitive Impairment Considering APOE ε4: A Prospective Cohort Study. J Prev Alzheimers Dis, 2024; 11(3): 582-588.

3.Zhou D, Sun Y, Qian Z, Wang Z, Zhang D, Li Z, Zhao J, Dong C, Li W*, Huang G*. Long-term dietary folic acid supplementation attenuated aging-induced hippocampus atrophy and promoted glucose uptake in 25-month-old rats with cognitive decline. J Nutr Biochem, 2023, 21: 109328. 

4.Yongjie Chen, Boran Sun, Caihong Wang, Keming Zhang, Wenli Lu*, Guowei Huang*. Associations of types of grains and lifestyle with all-cause mortality among Chinese adults aged 65 years or older: a prospective cohort study. J Transl Med, 2023, 21(1): 88. 

5.Qian Liu#, Zhenshu Li#, Ling Huang#, Dezheng Zhou, Jingzhu Fu, Huilian Duan, Zehao Wang, Tong Yang, Jing Zhao, Wen Li, Huan Liu, Fei Ma, Changqing Sun, Guangshun Wang, Yue Du, Meilin Zhang, Yongjie Chen*, Guowei Huang*. Telomere and mitochondria mediated the association between dietary inflammatory index and mild cognitive impairment: A prospective cohort study. Immun Ageing, 2023, 20(1): 1.

6.Jingzhu Fu#, Yun Zhu#, Yue Sun, Qian Liu, Huilian Duan Ling Huang, Dezheng Zhou, Zehao Wang, Jing Zhao, Zhenshu Li, Yue Du, Huan Liu, Fei M, Yongjie Chen, Changqing Sun, Guangshun Wang, Wen Li*, Guowei Huang*. Circulating Amyloid-β and Methionine-Related Metabolites to Predict the Risk of Mild Cognitive Impairment: A Nested Case-Control Study. J Alzheimers Dis, 2022, 9: 389-404. 

7.Jing Yan, Qinghan Ren, Hongyan Lin, Qian Liu, Jingzhu Fu, Changqing Sun, Wen Li, Fei Ma, Yun Zhu, Zhenshu Li, Guoquan Zhang, Yue Du, Huan Liu, Xumei Zhang, Yongjie Chen, Guangshun Wang, Guowei Huang*. Association between dietary patterns and the risk of depressive symptoms in the older adults in rural China. Nutrients, 2022, 14: 3538. 

8.Jingzhu Fu#, Qian Liu#, Yun Zhu#, Changqing Sun, Huilian Duan, Ling Huang, Dezheng Zhou, Zehao Wang, Jing Zhao, Zhenshu Li, Fei Ma, Wen Li, Huan Liu, Xumei Zhang, Yongjie Chen, Guangshun Wang, Yue Du*, Guowei Huang*. Circulating folate concentrations and the risk of mild cognitive impairment: A prospective study on the older Chinese population without folic acid fortification. Eur J Neurol, 2022, 29(10): 2913-2924.

9.Huilian Duan, Yue Sun, Jingzhu Fu, Qian Liu, Ling Huang, Zehao Wang, Jing Zhao, Zhenshu Li, Wen Li, Huan Liu, Fei Ma, Yongjie Chen, Changqing Sun, Guangshun Wang, Yue Du*, Guowei Huang*. APOEε4-stratified longitudinal association between daytime nap, sleep apnea and mild cognitive impairment: a prospective cohort study. Eur J Neurol, 2022, 29(5): 1385-1393.

10.Zhenshu Li#, Wen Li#, Dezheng Zhou, Jing Zhao,Yue Ma, Ling Huang, Cuixia Dong, John X. Wilson, Guowei Huang*. Alleviating oxidative damage-induced telomere attrition: a potential mechanism for inhibition by folic acid of apoptosis in neural stem cells. Mol Neurobiol, 2022, 59(1): 590-602.

11.Zhenshu Li#, Dezheng Zhou#, Dalong Zhang#, Jing Zhao, Wen Li, Yue Sun,Yongjie Chen, Huan Liu, John X Wilson, Zhiyong Qian*, Guowei Huang*. Folic Acid Inhibits Aging-Induced Telomere Attrition and Apoptosis in Astrocytes In Vivo and In Vitro. Cereb Cortex, 2022, 32(2): 286-297. 

12.Dezheng Zhou, Xin Lv, Yalan Wang, Huan Liu, Suhui Luo, Wen Li*, Guowei Huang*. Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism. J Nutr Biochem, 2021, 97: 108796.

13.Yongjie Chen#, Yue Du#, Zhuoyu Sun#, Qian Liu, Changqing Sun, Hongyan Lin, Mengdi Jin, Jingzhu Fu, Fei Ma, Wen Li, Huan Liu, Xumei Zhang, Guangshun Wang∗, Guowei Huang*. Interactions Between Handgrip Strength and Serum Folate and Homocysteine Levels on Cognitive Function in the Elderly Chinese Population. J Alzheimers Dis, 2021, 80(4): 1503-1513.

14.Mengyue Li#, Wen Li#, Yiming Gao, Yongjie Chen, Dong Bai, Jinxi Weng, Yue Du, Fei Ma, Xinyan Wang, Huan Liu*, Guowei Huang*. Effect of folic acid combined with docosahexaenoic acid intervention on mild cognitive impairment in elderly: a randomized double-blind, placebo-controlled trial. Eur J Nutr, 2021, 60(4): 1795-1808. 

15.Chen H#, Liu S#, Ge B, Zhou D, Li M, Li W, Ma F, Liu Z, Ji Y*, Huang G*. Effects of Folic Acid and Vitamin B12 Supplementation on Cognitive Impairment and Inflammation in Patients with Alzheimer’s Disease: A Randomized, Single-Blinded, Placebo-Controlled Trial. J Prev Alz Dis, 2021, 8(3): 249-256. 

Grants

1.National Natural Science Foundation of China, Principal Investigator: Double-edged sword effects of folic acid on the incidence of colorectal cancer and the mechanism of DNA thymidine acid synthesis (Grant Number: 82373571), 2023.01-2027.12, 490,000RMB.

2.National Natural Science Foundation of China, Principal Investigator: Effects of medium chain triglycerides combined with DHA on ameliorating cognitive decline by brain energy metabolism in mild cognitive impairment (Grant Number: 82073547), 2021.01-2024.12, 590,000RMB.

3.Chinese Nutrition Society-National Nutrition Science Research Grant, Principal Investigator: Construction and application of dietary pattern with Chinese characteristics to reduce the risk of cardiovascular metabolic disease (Grant Number: CNS-NNSRG2022-149), 2022.09-2024.12, 980,000RMB .

4.National Key Research and Development Program projects of China, Sub-project: Application of dietary intervention and evaluation plan for cognitive function decline in the elderly (Grant Number: 2022YFC2010100), 2022.07-2025.06, 260,000RMB. 

5.Research Project of BY-HEALTH Co., Ltd, Principal Investigator: Study on the intervention effects of BY-HEALTH (R) phosphatidylserine ginkgo leaf soft capsules on elderly with mild cognitive impairment (Grant Number: C01202108020003), 2021.09-2024.06, 1500,000RMB.

6.Key Project of National Natural Science Foundation of China, Principal Investigator: Effects of folate on the apoptosis of neurocytes and delaying cognitive decline by telomeres in older people (Grant Number: 81730091), 2018.01-2022.12, 3000,000 RMB.

7.National Natural Science Foundation of China, Principal Investigator: Epigenetic effects of folic acid on brain development by DNA methylation (Grant Number: 81472967), 2015.01-2018.12, 900,000RMB.

8.Tianjin Science and Technology Support Program: Principal Investigator. Project Title: Intervention study of folic acid and vitamin B12 on the patients with Alzheimer’s disease in community (Grant Number: 15ZCZDSY01040), 2015-2018, 300,000RMB.