Tianjin Qiao, W, PhD
Professor
College of Pharmacy
Tianjin Medical University
22 Qixiangtai Road
Tianjin 300070
Email: qiaowei@tmu.edu.cn
Education
MD Tianjin Medical University, Tianjin, China, 2002
Ph.D. Tianjin Medical University, Tianjin, China, 2009
Professional Experience
1991-2000 Instructor, College of Pharmacy, Tianjin Medical University, Tianjin, China
2002-2011 Associate Professor, College of Pharmacy, Tianjin Medical University, Tianjin, China
2011- Professor, College of Pharmacy , Tianjin Medical University, Tianjin, China
Research Interest
1. Discovery and elucidation the mechanism of action of antidepressant, sedative-hypnotic active components from traditional Chinese medicine.
2. Design, synthesis and molecular docking studies of novel lead compound derivatives with antidepressant and sedative-hypnotic action.
3. Development of novel formulations of effective constituent for the treatment of central nervous system diseases.
Professional Service
Membership of Academic Society
Tianjin Association of Integrative Medicine
Pharmaceutical Professional Committee of Tianjin Medical and Health Association
Books
Ø New Technology Used For Extraction and Separation of Traditional Chinese medicine，Deputy Editor, 2010, Science Press
Ø The Medicinal Chemistry of Natural Products (second edition), Editorial Board, 2015, Higher Education Press
Ø The Medicinal Chemistry of Natural Products , Editorial Board, 2013, People's Medical Publishing House
Ø The Medicinal Chemistry of Natural Products , Editorial Board, 2012, Higher Education Press
Ø Separation and Purification Technology of Medicine, 2009, Chemical Industry Press
Publication
1. Hao Xu, Yuyu Niu, Yan Sun, Menglin Xia, Daozheng Lin, Wei Qiao*. Separation and purification of magnoflorine, spinosin,and 6‴-feruloyspinosin from Ziziphi Spinosae Semen by high-speed counter-current chromatography. Journal of Separation Science 2021;1–8
2. SUN Dan-chen, WANG Ran-ran, XU Hao, ZHU Xue-hui, SUN Yan, QIAO Shi-qing, QIAO Wei*. A Network Pharmacology-Based Study on the Antidepressant Effect of Salicornia europaea L. Extract with Experimental Support Using Chronic Unpredictable Mild Stress Model Mice. Chinese Journal of Integrative Medicine DOI: https://doi.org/10.1007/s11655-021-2879-7
3. Yongsheng Cui, Lixia Zhu, Yixuan Li, Siliang Jiang, Qili Sun, Enyi Xie, Hubiao Chen, Zhongzhen Zhao, Wei Qiao, Jun Xu**, Caixia Dong*.Antifouling activity against bryozoan and barnacle by cembrane diterpenes from the soft coral Sinularia flexibilis. Carbohydrate Polymers 2021; 255, 117389
4. Yong-Sheng Cui, Yi-Xuan Li, Si-Liang Jiang, An-Ning Song, Zheng Fu, Cai-Xia Dong, Zhi Yao*, Wei Qiao*. Isolation, purification, and structural characterization of polysaccharides from Atractylodis Macrocephalae Rhizoma and their immunostimulatory activity in RAW264.7 cells. International Journal of Biological Macromolecules 2020; 163, 270-278
5. Bingjie Li, Linmeng Han, Binyan Cao, Xiaoying Yang, Xuehui Zhu, Bing Yang, Haodong Zhao, Wei Qiao*. Use of magnoflorine-phospholipid complex to permeate blood-brain barrier and treat depression in the CUMS animal model.Drug Delivery 2019; 26(1), 566-574
6. Yan Liang , Xu Yang , Xiaojian Zhang , Hongquan Duan , Meina Jin , Yan Sun ,Hengjie Yuan , Junqiang Li, Yuedong Qi*, Wei Qiao*. Antidepressant -like effect of the saponins part of ethanol extract from SHF. Journal of Ethnopharmacology 2016; 191, 307-314
7. Shuang Zheng, Ming-Liang Chang, Jing Zhou, Jingwei Fu, Qing-Wei Zhang, Shao-Yong Li*, W Qiao*, Jun-Min Liu*.Qualitative Analysis of the Helical Electronic Energy of Inherently Chiral Calix[4]arenes:An Approach to Effectively Assign Their Absolute Configuration. International Journal of Molecular Sciences 2014;15, 9844-9858
8. Yan Sun, Fei Meng, Zhaohui Chen, Qingwei Zhang, Wei Qiao*, Wen Zhou, Xue Qin. Antidepressant-like effects of the total alkaloids from Semen Zizyphi Sponosae in mice models of depression. Pharmacologia2013; 4(12), 634-640
9. Jingshu Liu, Wei Qiao*, Yi Yang, Liyan Ren, Yan Sun, Shaoxun Wang. Antidepressant like effect of the ethanolic extract from Suanzaorenhehuan Formula in mice models of depression. Journal of Ethnopharmacology2012; 141, 257-264
10. Wei Qiao*, Jingshu Liu, Lu Li, Yi Yang, Liyan Ren. Antidepressant-like effect of total alkaloids extracted from Semen Zizyphi Sponosae, 2011 International Conference on Bioengineering，Chemistry and Environment Science, 2011,10:8061
11. Wei Qiao, Chuan Zhao, Nan Qin, Huiyuan Zhai, Hongquan Duan*. Identification of trans- tiliroside as active principle with anti-hyperglycemic, antihyperlipidemic and antioxidant effects from Potentilla chinesis.Journal of Ethnopharmacology, 2011, 135:515-521
12. Nan Qin, Ying Chen, Meian Jin, Chang Zhang, Xiaolong Yue, Wei Qiao, Hongquan Duan*, Wenyan Niu*. Anti-obesity and anti-diabetic effects of flavonoid derivative(Fla-CN) via microRNA in high fat diet induced obesity mice. European Journal of Pharmaceutical Sciences, 2016, 82:52-63
13. Ying Chen, Chang Zhang, Meina Jin, Nan Qin, Xiaolong Yue, Wei Qiao, Hongquan Duan*, Wenyan Niu*. Flavonoid derivative exerts antidiabetic effect via AMPK activation in diet-induced obesity mice. Natural Product Research ,2016; 30(17):1988-1992
14. Mei-Na Jin, Guo-Rui Shi, Sheng-An Tang, NanQin, Wei Qiao, Hong-Quan Duan*. Flavonoids from Tetrastigma obtectum enhancing glucose consumption in insulin-resistance HepG2 cells via activatingAMPK, Fitoterapia, 2013;90:240-246
Grant
2017.4-2020.3 Tianjin Research Program of Applied Basic and Cutting-edge Technologies Study on the effective components' aporphine quartermary ammonium alkaloids- flavonoid C-glycosides' insemen Ziziphi spinosae and its synergistic mechanism for treatment of depression with insomnia.
2012.1-2015.12 The National Natural Science of China fund project Study on the material base and mechanism of depression-relieving and spirit-quieting from semen zizyphi spinosae.
2012.4-2015.3 Tianjin Research Program of Applied Basic and Cutting-edge Technologies Study on the pharmacologic activity and mechanism of flavonoid derivative from Potentilla chinensis Ser.
