Huan Liu Associate Professor
Department of Nutrition and Food Science
Email liuhuan@tmu.edu.cn
Resume
Huan Liu, Ph.D., associate professor, supervisor of master student, vice director of the Central Laboratory in School of Public Health. Second levels of 131 innovative talents training project in Tianjin. The main research direction is nutrition and neurodegenerative diseases. In recent years, she has hosted a National Natural Science Foundation of China, participated in four National Natural Science Foundations. More than 10 SCI papers in international academic journals such as J Nutr Biochem and Eur J Nutr has been published. She published 2 textbooks as the subeditor, and participated in editing 3 textbooks. She has won the second prize in Tianjin University Young Teachers Basic Skill Competition.
Research direction
Nutrition and neurodegenerative diseases
Education
1. 1998/09–2003/07 Sun Yat-Sen University, B.S
2. 2003/09–2006/07 Tianjin Medical University, Nutrition and Food Hygiene, M.D.
3. 2008/09–2011/07 Tianjin Medical University, Epidemiology and Health Statistics (Nutrition Direction), Ph.D.
Professional Experience
1. 2014-2015 Visiting Scholar, Cornell University, NY, US
2. 2013- Associate Professor, Department of Nutrition and Food Science, Tianjin Medical University, Tianjin, China
3. 2008-2013 Lecturer, Department of Nutrition and Food Science, Tianjin Medical University, Tianjin, China
4. 2006-2008 Assistant, Department of Child and Adolescent Health, Tianjin Medical University, Tianjin, China
Project
1. Study on the effects of folic acid on neural stem cells of transgenic AD mice based on microRNA mechanism., the National Natural Science Foundation of China, 81202200, 230,000 yuan, 2013/01-2015/12, Project principal.
2. The study of the product improving sleep function, Tomson Bianjian Co., Ltd. commissioned the project, 70,000 yuan, 2018.01-2018.12, Project principal.
3. The mechanism of folic acid affecting cognitive function after cerebral infarction based on lncRNA and NMDA receptor regulation of synaptic plasticity, National Natural Science Foundation of China, 81874262, 580,000 yuan, 2019/01-2022/12, Participant.
4. The anti-aging mechanism of astaxanthin based on autophagy regulation mechanism, Tomson Bianjian Nutritional Science Research Fund, TY0181104, 2019/01-2020/12, 450,000 yuan, Participant.
5. The intervention effect of folic acid and DHA on the elderly with mild cognitive impairment, Tomson Bianjian Nutritional Science Research Fund, TY0151102, 300,000 yuan, 2016/01-2019/06, Participant.
6. The effect of a health care product on depression, Tomson Bianjian Co., Ltd. commissioned a project, 450,000 yuan, 2017/09-2019/09, Participant.
7. The mechanism of homocysteine on the proliferation and differentiation of neural stem cells by DNA methylation pathway, National Natural Science Foundation of China, 81373003, 800,000 yuan, 2014/01-2017/12, Participant.
8. The mechanism of folic acid on Alzheimer's disease based on the DNA methylation pathway, the National Natural Science Foundation of China, 81130053, 2.6 million yuan, 2012/01-2016/12, Participant.
9. The epigenetic mechanism of folic acid on neural stem cells based on the DNA methylation of, the National Natural Science Foundation of China, 81072289, 330,000 yuan, 2011/01-2013/12, Participant.
Publication
(1) Tian T, Bai D, Li W, Huang GW, Liu H*. Effects of Folic Acid on Secretases Involved in A Deposition in APP/PS1 Mice，Nutrients. 2016 Sep 9;8(9). pii: E556. doi: 10.3390 /nu8090556
(2) Zheng M, Zou C, Li M, Huang G, Gao Y, Liu H*. Folic Acid Reduces Tau Phosphorylation by Regulating PP2A Methylation in Streptozotocin- Induced Diabetic Mice. Int J Mol Sci. 2017 Apr 19;18(4). pii: E861. doi: 10.3390/ijms18040861
(3) Liu H#, Tian T, Qin S, Li W, Zhang X, Wang X, Gao Y, Huang G*，Folic acid deficiency enhances abeta accumulation in APP/PS1 mice brain and decreases amyloid-associated miRNAs expression. J Nutr Biochem. 2015,26(12):1502-8
(4) Liu H#, Li W#, Zhao S, Zhang X, Zhang M, Xiao Y, Wilson JX, Huang G*，Folic acid attenuates the effects of amyloid beta oligomers on DNA methylation in neuronal cells. Eur J Nutr. 2016,55(5):1849-62
(5) Liu H#, Cao J#, Zhang H, Qin S, Yu M, Zhang X, Wang X, Gao Y, Wilson JX, Huang G*. Folic acid stimulates proliferation of transplanted neural stem cells after focal cerebral ischemia in rats，J Nutr Biochem. 2013,24(11):1817-22.
Postgraduate training
1 master's has graduated; 4 master's students are studying
Recruits students specialized
Nutrition and food hygiene
Textbooks
1. Response and Disposal of Public Health Emergencies, Peking University Medical Press (Associate editor)
2. Basic Nutrition and Dietary Therapy (English adapted version), Tsinghua University Press (Associate editor)
3. Modern Food Hygiene (2nd Edition), People's Medical Publishing House (Participation)
4. Nutrition and Food Hygiene (Case Edition) 2nd Edition, Science Press (Participation)
5. Comprehensive Experiments for Preventive Medicine and Public Health, Peking University Medical Press (Participation)
Membership of Academic Society
Tianjin Nutrition Institute (Director)
Tianjin Food Institute (Director)
Honors
1. Second Prize of National Teaching Achievement Award for Higher Education (Fourth Completion), 2018
2. First Prize of Tianjin Teaching Achievements for Higher Education (Fourth Completion), 2018
3. Excellent Teacher Development Support Program, Tianjin Medical University, 2018
4. Education and Teaching Excellence Award, Tianjin Medical University, 2018
5. The 13th Tianjin University Young Teachers Basic Skill Competition, Second Prize, 2016
6. Second levels of 131 innovative talents training project in Tianjin, 2015
7. The project of “Excellent Young Teachers Funding Program” in Tianjin, 2013
8. Excellent Graduation Design for Undergraduates in Tianjin Universities, as supervisor, 2011
