Wen Li Associate Professor
Department of nutrition and food hygiene
Emailliwen828@tmu.edu.cn
Resume
Wen Li, associate professor, PhD, Department of nutrition and food hygiene, school of public health, Tianjin Medical University. She has participated in 8 projects of the National Natural Science Foundation, and is currently presiding over 1 youth project of the National Natural Science Foundation. As a major research member, she has participated in 1 key project and 1 project on the surface of the National Natural Science Foundation. As first author or co-first author, she has published 13 academic papers, of which 7 SCI papers as first author, and 2 SCI papers as co-first author (cumulative impact factors 30 points). As first author she has published 2 papers in Chinese core journals and 2 teaching papers. Selected for the China Association for Science and Technology Youth Talent Lift Project and Tianjin Youth Talent Lift Project, was selected as the third level of 131 innovative talents in Tianjin.
Research direction
Education
2010.09~2015.07: PhD in Nutrition and Food Hygiene,Tianjin Medical University, Tianjin, China
2005.09~2010.07: Bachelor'sin Medicine, Tianjin Medical University, Tianjin, China
Professional Experience
2018.12~present: Associate Professor, Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China
2015.07~2018.12: Lecturer, Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, China
Project
Publication
1.Wen Li, Zhenshu Li (co-first author), Dezheng Zhou, Xumei Zhang, Jing Yan, Guowei Huang*. Maternal Folic Acid Deficiency Stimulates Neural Cell Apoptosis via miR-34a Associated with Bcl-2 in the Rat Foetal Brain. International Journal of Developmental Neuroscience. 2018 Nov 14;72:6-12. doi: 10.1016/j.ijdevneu.2018.11.002. (IF：2.495/2.559，Q2）
2.Wen Li, Zhenshu Li, Shou Li, Xinyan Wang, John X. Wilson, Guowei Huang*. Periconceptional Folic Acid Supplementation Benefit to Development of Early Sensory-Motor Function through Increase DNA Methylation in Rat Offspring. Nutrients. 2018 Mar 1;10(3). pii: E292. doi: 10.3390/nu10030292. (IF：4.196/4.603，Q1）
3.Wen Li, Huan Liu, Min Yu, Xumei Zhang, Yan Zhang, Hongbo Liu, John X. Wilson, Guowei Huang*. Folic acid alters methylation profile of JAK-STAT and long-term depression signaling pathways in Alzheimer’s disease models. Molecular Neurobiology. 2016; 53(9), 6548-6556. DOI: 10.1007/s12035-015-9556-9. (IF：5.076/5.136，Q1）
4.Wen Li, Mingyue Jiang, Shijing Zhao, Huan Liu, Xumei Zhang, John X. Wilson, Guowei Huang*. Folic Acid Inhibits Amyloid β-Peptide Production through Modulating DNA Methyltransferase Activity in N2a-APP Cells. International Journal of Molecular Sciences. 2015,16(10):25002-25013. doi:10.3390/ijms161025002. (IF：3.687/3.878，Q2）
5.Huan Liu, Wen Li (co-first author), Shijing Zhao, Xumei Zhang, Meilin Zhang, Yanyu Xiao, John X. Wilson, Guowei Huang*. Folic acid attenuates the effects of amyloid β oligomers on DNA methylation in neuronal cells. European Journal of Nutrition. 2015;55(5):1849-1862. DOI: 10.1007/s00394-015-1002-2.（IF：4.423/4.125，Q1）
6.Wen Li, Huan Liu, Min Yu, Xumei Zhang, Meilin Zhang, John X. Wilson, Guowei Huang*. Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice. Journal of Nutritional Biochemistry. 2015;26(8):883-891. doi: 10.1016/j.jnutbio.2015.03.009. (IF：4.414/4.669，Q1）
7.Wen Li, Mingyue Jiang, Yanyu Xiao, Xumei Zhang, Shanshan Cui, Guowei Huang*. Folic acid inhibits tau phosphorylation through regulation of PP2A methylation in SH-SY5Y cells. Journal of Nutrition Health and Aging. 2015;19(2):123-129. doi: 10.1007/s12603-014-0514-4. （IF：2.868/3.199，Q2）
8.Wen Li, Min Yu (co-first author), Suhui Luo, Huan Liu, Yuxia Gao, John X. Wilson, Guowei Huang*. DNA methyltransferase mediates dose-dependent stimulation of neural stem cell proliferation by folate. Journal of Nutritional Biochemistry. 2013;4(7): 1295-1301. doi: 10.1016/j.jnutbio.2012.11.001.（IF：4.414/4.669，Q1）
9.Min Yu, Wen Li (co-first author), Suhui Luo, Yan Zhang, Huan Liu, Yuxia Gao, Xuan Wang, John X Wilson, Guowei Huang*. Folic acid stimulation of neural stem cell proliferation is associated with altered methylation profile of PI3K/Akt/CREB. Journal of Nutritional Biochemistry. 2014;25(4):496-502. doi: 10.1016/j.jnutbio.2013.12.010. （IF：4.414/4.669，Q1）
Membership of Academic Society
Membership of Chinese Society of Nutrition
Honors